Our immune system is built to communicate what's going on.
Our mission is to listen.
MeMed’s host response technology decodes the complex signals of our immune system into actionable insights. These can be used to transform the way infectious diseases are diagnosed and treated.
MeMed started by focusing on a "seemingly" simple problem, a patient with FEVER, which leads to some of the biggest healthcare challenges of our time.
Fever dilemma #1:
Is an infection bacterial or viral?
To treat or not to treat with antibiotics?
Fever dilemma #2:
Is the condition severe or not?
To escalate treatment or not?
The first clinical dilemma we help address:
Bacterial or viral?
Since bacterial and viral infections are clinically indistinguishable, physicians are often challenged to decide whether to treat or not with antibiotics. By providing host response information, we help physicians make more informed decisions about how and when to treat.
3 Biomarkers + Machine Learning
= MeMed BV
From a small serum sample, MeMed BV computationally integrates the levels of three host immune response proteins (TRAIL, IP-10 and CRP) into a simple score indicating the likelihood of a bacterial or viral infection.
The first B vs. V test clinically validated to the highest standard with studies that are:
• Double blind
Accuracy and Reliability
PPA (Positive Percent Agreement) =
True positive / (True Positive + False Negative)
NPA (Negative Percent Agreement) =
True Negative / (True Negative + False Positive)
*8.3% of the patients had an equivocal score result
Conventional tests are often insufficient because...
Prolonged time to results
Inaccessible infection sites
Often no pathogens
False alarms due to colonization
Uncertainty regarding severity
The Power of the Platform
MeMed Key makes it possible to conduct highly sensitive, rapid, multiplexed protein measurements at the point of need that previously could only be done on central lab equipment. MeMed Key is a compact immunoassay platform which can run the MeMed BV test distinguishing between bacterial and viral infections in just 15 minutes.
Compact: Height 9.84 in. | Weight 9.84 in. | Depth 13.4 in. | Weight 17 lb.
MeMed BV & MeMed Key: CE Marked & FDA cleared
MeMed COVID 19 Severity: under development
COVID-19 Severity is not cleared by the FDA for any indication. COVID-19 Severity is not currently available for sale in the US.
1. Data on file. Apollo Clinical Study (NCT04690569) conducted to establish the diagnostic performance of the MeMed BV Test for differentiating bacterial from viral infection in patients with suspected acute bacterial or viral infection. 2. Oved, K. et al. PLoS One (2015) 3. van Houten, C. B. et al. OPPORTUNITY: Lancet Infect. Dis. (2016). 4. Srugo, I. et al. Pediatrics (2017) 5. Ashkenazi-Hoffnung, L. et al. EJC MID (2018) 6. Stein et al. Diagn Microbiol Infect Dis. (2017) 7. Eden et al. Department. J Infect. (2016)